What are Bone Marrow Failure Syndromes? 
Bone Marrow Failure Syndromes (BMFS) are a collection of immune system related medical conditions that cause the bone marrow stem cells to reduce or stop the production of healthy red blood cells, white blood cells, and platelets needed by the body. Bone marrow failure can be acquired by previously healthy people or inherited genetically through the family.  Some people can manage their Bone Marrow Failure Syndromes through existing treatments, but the only established cure is a bone marrow transplant.  Our research aims to uncover the genetic causes of this failure in bone marrow and circulating blood cells, and the insight from this work will lead to the identification of indicators for disease profiling and the development of better treatments.